Thalamocortical Synapses
نویسندگان
چکیده
منابع مشابه
Thalamocortical Synapses Sparse but Stentorian
occurs with a probability close to 1, and the open proba-by NMDARs (Gomperts et al., 1998). Finally, a study of bility of NMDARs when bound by glutamate is high. the rise time of the NMDAR response at silent synapses Finally, the lack of effect of glutamate uptake blockers failed to find a slowing as would be expected and, in on the response suggests that glutamate is near satu-fact, was found ...
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During development, activity-dependent mechanisms are thought to contribute to the refinement of topographical projections from the thalamus to the cortex. Because activity-dependent increases in synaptic strength may contribute to the stabilization of synaptic connections, we have explored the mechanisms of long-term potentiation (LTP) at thalamocortical synapses in rat somatosensory (barrel) ...
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Sensory stimuli reach the brain via the thalamocortical projection, a group of axons thought to be among the most powerful in the neocortex. Surprisingly, these axons account for only approximately 15% of synapses onto cortical neurons. The thalamocortical pathway might thus achieve its effectiveness via high-efficacy thalamocortical synapses or via amplification within cortical layer 4. In rat...
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Neuronal adaptation to repetitive sensory stimuli is ubiquitous in the mammalian cortex. Despite its prevalence, the cellular mechanisms underlying this basic physiological property remain a matter of dispute. In this issue of Neuron, Chung et al. provide conclusive evidence that depression of thalamocortical synapses may play a significant role in the expression of neuronal adaptation in the r...
متن کاملPresynaptic gating of postsynaptically expressed plasticity at mature thalamocortical synapses.
Thalamocortical (TC) projections provide the major pathway for ascending sensory information to the mammalian neocortex. Arrays of these projections form synaptic inputs on thalamorecipient neurons, thus contributing to the formation of receptive fields (RFs) in sensory cortices. Experience-dependent plasticity of RFs persists throughout an organism's life span but in adults requires activation...
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ژورنال
عنوان ژورنال: Neuron
سال: 1999
ISSN: 0896-6273
DOI: 10.1016/s0896-6273(00)80770-9